Novel Model To Study Virulence Determinants of Escherichia coli K1
نویسندگان
چکیده
منابع مشابه
Novel model to study virulence determinants of Escherichia coli K1.
It is shown here for the first time that locusts can be used as a model to study Escherichia coli K1 pathogenesis. E. coli K-12 strain HB101 has very low pathogenicity to locusts and does not invade the locust brain, whereas the injection of 2 x 10(6) E. coli K1 strain RS218 (O18:K1:H7) kills almost 100% of locusts within 72 h and invades the brain within 24 h of injection. Both mortality and i...
متن کاملthe association of virulence determinants of uropathogenic escherichia coli with antibiotic resistance
conclusions the results showed that e. coli isolated from patients with uti had eight virulence factors with high frequencies. moreover, these results alleged a direct connection between virulence factors and antimicrobial resistance in e. coli. results the frequency of virulence factors papc, afa, sfa/foc, fimh, hly, neuc, ibea, and iucc were 53.3%, 51.7%, 53.3%, 56.7%, 23.3%, 31.7%, 20%, and ...
متن کاملA study on association of virulence determinants of verotoxic Escherichia coli isolated from cattle calves
AIM The present study was conducted to find the association among virulence determinants of verotoxic Escherichia coli (VTEC) isolated from cattle calf feces. MATERIALS AND METHODS A total of 216 cattle calf fecal samples were collected aseptically and processed under required conditions for the isolation of E. coli. The isolates were further subjected to multiplex polymerase chain reaction (...
متن کاملCTX-M β-Lactamase Production and Virulence of Escherichia coli K1
We report a patient with neonatal meningitis caused by a CTX-M-1-producing Escherichia coli K1 strain. The influence of CTX-M production on virulence was investigated in cell culture and a newborn mouse model of meningitis. CTX-M production had no influence on virulence but was a major factor in clinical outcome.
متن کاملVirulence patterns of Escherichia coli K1 strains associated with neonatal meningitis.
The prevalence of the ibe10 gene, of the pap, afa, and sfa adhesin-encoding operons, and of a 14.9-kb rrn-containing HindIII fragment was studied for 67 Escherichia coli neonatal meningitis strains, 58 E. coli K1 commensal strains, and 47 E. coli blood isolates from neonates without meningitis. ibe10, sfa, and the 14.9-kb HindIII fragment were observed significantly more often in the meningitis...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2007
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.00740-07